The letters in ASSUMING make 142 words of two letters or more. The longest is ASSUMING at 8 letters, and the highest-scoring is ASSUMING at 11 points.
No other single word uses all 8 letters of ASSUMING. ASSUMING has 8 letters: 3 vowels and 5 consonants, worth 11 points before any board bonuses.
8-letter words 1
7-letter words 4
6-letter words 6
agisms9animus8assign7gamins9musing9sigmas9
5-letter words 29
agism8amins7amiss7gains6gamin8gaums8gauss6guans6magus8mains7manus7minas7minus7munis7nisus5sagum8sains5sangs6sasin5sigma8signs6simas7sings6sinus5snags6snugs6suing6unais5using6
4-letter words 48
agin5aims6ains4amin6amis6amus6anis4gain5gams7gaum7gaun5gins5gnus5guan5gums7isms6magi7mags7main6mans6mass6maun6migs7mina6miss6mugs7muni6muns6muss6nags5nims6sags5sain4sang5sans4sign5sima6sims6sing5sins4smug7snag5snug5sums6sung5suns4unai4unis4
3-letter words 35
aim5ain3ais3ami5amu5ani3gam6gan4gas4gin4gnu4gum6ins3ism5mag6man5mas5mig6mis5mug6mun5mus5nag4nam5nim5nus3sag4sau3sim5sin3sis3sum5sun3uni3uns3
2-letter words 19
ag3ai2am4an2as2gs3in2is2ma4mi4ms4mu4na2nu2si2ss2um4un2us2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.