The letters in CREATURE make 116 words of two letters or more. The longest is CREATURE at 8 letters, and the highest-scoring is CREATURE at 10 points.
No other single word uses all 8 letters of CREATURE. CREATURE has 8 letters: 4 vowels and 4 consonants, worth 10 points before any board bonuses.
8-letter words 1
7-letter words 4
caterer9recrate9retrace9terrace9
6-letter words 15
acuter8career8carter8cerate8crater8create8curare8curate8curter8ecarte8retear6tearer6terrae6tracer8ureter6
5-letter words 29
acute7arete5carer7caret7carte7cater7crate7cruet7crura7curer7curet7cuter7eater5erect7eruct7racer7rater5react7recta7recur7recut7tarre5terce7terra5trace7truce7truer5urare5urate5
4-letter words 25
acre6care6carr6cart6cate6cere6cete6cree6cure6curr6curt6cute6ecru6race6rare4rate4rear4rete4ruer4tace6tare4tear4tree4true4urea4
3-letter words 34
ace5act5arc5are3art3ate3car5cat5cee5cru5cue5cur5cut5ear3eat3eau3ecu5era3ere3err3ert3eta3rat3rec5ree3ret3rue3rut3tae3tar3tau3tea3tee3uta3
2-letter words 8
ae2ar2at2er2et2re2ta2ut2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.