The letters in EXISTENCE make 113 words of two letters or more. The longest is EXISTENCE at 9 letters, and the highest-scoring is EXISTENCE at 18 points.
No other single word uses all 9 letters of EXISTENCE. EXISTENCE has 9 letters: 4 vowels and 5 consonants, worth 18 points before any board bonuses.
9-letter words 1
7-letter words 3
entices9excites16sixteen14
6-letter words 9
5-letter words 27
cense7cents7cesti7cetes7cines7cites7execs14exine12exist12exits12inset5neist5niece7nites5nixes12scene7scent7seine5sente5senti5since7sixte12stein5teens5tense5tines5xenic14
4-letter words 34
cees6cent6cete6cine6cist6cite6etic6exec13exes11exit11ices6nest4nets4next11nice6nite4nits4nixe11sect6seen4sene4sent4sext11sice6sine4site4snit4teen4tees4tens4tics6ties4tine4tins4
3-letter words 26
cee5cis5ens3ice5ins3its3nee3net3nit3nix10sec5see3sei3sen3set3sic5sin3sit3six10tee3ten3tic5tie3tin3tis3xis10
2-letter words 13
cs4en2es2et2ex9in2is2it2ne2si2ti2ts2xi9
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.