There are 59 words hidden in the letters of HANDLE, from 16 two-letter words up to HANDLE (6 letters). For points, HANDLE is best at 10.
No other single word uses all 6 letters of HANDLE. HANDLE has 6 letters: 2 vowels and 4 consonants, worth 10 points before any board bonuses.
6-letter words 1
5-letter words 4
eland6haled9laden6naled6
4-letter words 20
dahl8dale5deal5dean5dhal8elan4hade8haed8haen7hale7hand8head8heal7held8lade5land5lane4lead5lean4lend5
3-letter words 18
ale3and4ane3dah7dal4del4den4edh7eld4end4had7hae6hen6lad4lea3led4nae3nah6
2-letter words 16
ad3ae2ah5al2an2de3ed3eh5el2en2ha5he5la2ln2na2ne2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.