The letters in HUNDREDS make 127 words of two letters or more. The longest is HUNDREDS at 8 letters, and the highest-scoring is HUNDREDS at 13 points.
No other single word uses all 8 letters of HUNDREDS. HUNDREDS has 8 letters: 2 vowels and 6 consonants, worth 13 points before any board bonuses.
8-letter words 1
7-letter words 2
hundred12shudder12
6-letter words 7
5-letter words 23
druse6dudes7dunes6dured7dures6durns6herds9herns8hurds9nerds6nuder6nurds6nurse5redds7rends6rudds7runes5shend9sherd9shred9udder7under6usher8
4-letter words 49
dens5dude6duds6dues5dune5duns5dure5durn5edhs8ends5erns4ersh7hens7herd8hern7hers7hued8hues7huns7nerd5nurd5redd6reds5rend5resh7rhus7rudd6rude5rued5rues4rune4runs4ruse4rush7send5shed8sher7shun7sned5sudd6sued5suer4surd5sure4unde5urds5urns4used5user4
3-letter words 30
den4dud5due4duh7dun4edh7end4ens3ern3ers3hen6her6hes6hue6hun6nus3red4res3rue3run3sen3ser3she6sud4sue3sun3uns3urd4urn3use3
2-letter words 15
de3ed3eh5en2er2es2he5ne2nu2re2rs2sh5uh5un2us2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.