The letters in ISOLATING make 349 words of two letters or more. The longest is INTAGLIOS at 9 letters, and the highest-scoring is INTAGLIOS at 10 points.
ISOLATING is an anagram of INTAGLIOS and LIGATIONS, using all 9 letters. ISOLATING has 9 letters: 4 vowels and 5 consonants, worth 10 points before any board bonuses.
Anagrams of ISOLATING 2
intaglios10ligations10
9-letter words 3
8-letter words 5
antilogs9intaglio9ligation9solating9tailings9
7-letter words 23
agonist8antilog8galiots8gitanos8intagli8lasting8latigos8latinos7liaison7listing8nilgais8sailing8salting8siloing8silting8slating8soiling8staling8tailing8talions7tiglons8tilings8toiling8
6-letter words 46
ailing7aiolis6algins7aligns7aloins6gainst7galiot7gaslit7giants7gitano7glints7gloats7ingots7instal6instil6isatin6isling7lasing7latigo7latino6liangs7ligans7lingas7logans7logins7losing7nilgai7oiling7santol6sating7sigloi7signal7siting7slogan7soling7stingo7talion6talons6tangos7tiglon7tigons7tiling7tolans6toling7tongas7tonsil6
5-letter words 81
agios6agist6agons6aioli5algin6align6alist5aloin5along6altos5angst6anils5antis5gains6gaits6gaols6giant6gilts6glans6glias6glint6gloat6glost6gnats6goals6goats6gonia6ingot6intis5iotas5liang6ligan6linga6lingo6lings6linos5lints5lions5litai5litas5loans5logan6logia6login6loins5longs6lotas5nails5noils5notal5ostia5saint5salon5santo5satin5sigil6slain5slang6slant5sling6snail5solan5staig6stain5stang6sting6stoai5tails5tains5talon5tango6tangs6tigon6tings6togas6toils5tolan5tolas5tonal5tonga6tongs6
4-letter words 110
agin5agio5agon5ails4ains4aits4alit4also4alto4alts4anil4anis4anti4ants4gain5gait5gals5gaol5gast5gats5gilt5gins5gist5gits5glia5gnat5goal5goas5goat5ilia4inia4inti4into4ions4iota4lags5lain4lang5last4lati4lats4ling5lino4lins4lint4lion4list4lits4loan4logs5loin4long5lost4lota4loti4lots4nags5nail4naoi4naos4nils4nisi4nits4nogs5noil4nota4oast4oats4oils4sago5sail4sain4salt4sang5sati4sial4sign5silo4silt4sing5slat4slit4slog5slot4snag5snit4snog5snot4soil4sola4soli4song5stag5stoa4tags5tail4tain4tali4tang5tans4taos4tils4ting5tins4toga5togs5toil4tola4tong5tons4
3-letter words 54
ago4ail3ain3ais3ait3als3alt3ani3ant3gal4gan4gas4gat4gin4git4goa4got4ins3ion3its3lag4las3lat3lin3lis3lit3log4lot3nag4nil3nit3nog4nos3not3oat3oil3ons3sag4sal3sat3sin3sit3sol3son3sot3tag4tan3tao3tas3til3tin3tis3tog4ton3
2-letter words 27
ag3ai2al2an2as2at2go3gs3in2is2it2la2li2ln2lo2ls2na2no2oi2on2os2si2so2ta2ti2to2ts2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.