There are 84 words hidden in the letters of ITSELF, from 12 two-letter words up to FILETS (6 letters). For points, FILETS is best at 9.
ITSELF is an anagram of FLIEST, STIFLE, FILETS and FLITES, using all 6 letters. ITSELF has 6 letters: 2 vowels and 4 consonants, worth 9 points before any board bonuses.
Anagrams of ITSELF 4
fliest9stifle9filets9flites9
6-letter words 5
5-letter words 13
feist8felts8files8filet8flies8flite8flits8islet5istle5lefts8lifts8stile5tiles5
4-letter words 31
efts7felt7fest7fets7file7fils7fist7fits7flit7isle4left7leis4lest4lets4lief7lies4life7lift7list4lite4lits4seif7self7sift7silt4site4slit4tels4ties4tile4tils4
3-letter words 23
efs6eft6elf6els3fet6fie6fil6fit6ifs6its3lei3let3lie3lis3lit3sei3sel3set3sit3tel3tie3til3tis3
2-letter words 12
ef5el2es2et2if5is2it2li2ls2si2ti2ts2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.