There are 53 words hidden in the letters of MAINLY, from 15 two-letter words up to MAINLY (6 letters). For points, MAINLY is best at 11.
No other single word uses all 6 letters of MAINLY. MAINLY has 6 letters: 2 vowels and 4 consonants, worth 11 points before any board bonuses.
6-letter words 1
5-letter words 3
inlay8liman7manly10
4-letter words 16
amin6amyl9anil4ayin7inly7lain4lima6limn6limy9liny7mail6main6many9mina6myna9nail4
3-letter words 18
ail3aim5ain3ami5ani3any6lam5lay6lin3man5may8mil5nam5nay6nil3nim5yam8yin6
2-letter words 15
ai2al2am4an2ay5in2la2li2lm4ln2ma4mi4my7na2ya5
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.