Unscrambling MECHANISM gives 289 words. MECHANISM is the longest, and MECHANISM scores the most at 18 points.
No other single word uses all 9 letters of MECHANISM. MECHANISM has 9 letters: 3 vowels and 6 consonants, worth 18 points before any board bonuses.
9-letter words 1
8-letter words 2
chammies17machines15
7-letter words 11
6-letter words 45
amices10amines8ammine10anemic10animes8ashmen11camise10casein8chaine11chains11chaise11chiasm13chimes13chinas11chines11cinema10cnemis10encash11haemic13haemin11hances11hemins11iceman10immane10immesh13incase8inches11inmesh11inseam8maches13maihem13mamies10manche13manics10mashie11mensch13mesian8miches13minces10naches11niches11sachem13samech13schema13semina8
5-letter words 61
aches10acmes9acnes7amens7amice9amies7amine7amins7amnic9anime7anise5ashen8cains7cames9canes7chain10chams12chase10chasm12chias10chime12china10chine10chins10cines7haems10hames10hance10hanse8hemic12hemin10imams9maces9mache12machs12maims9mains7mamie9manes7manic9manse7means7mensa7mesic9miasm9micas9miche12miens7mimes9minae7minas7mince9mines7names7nemas7niche10saice7scena7shame10shine8since7
4-letter words 85
aces6ache9acme8acne6ahem9aims6ains4amen6amie6amin6amis6anes4anis4asci6cain6came8cams8cane6cans6case6cash9cham11chia9chin9chis9cine6each9emic8haem9haen7haes7hame9hams9hems9hens7hies7hims9hins7hisn7ices6ichs9imam8inch9mace8mach11macs8maes6maim8main6mams8mane6mans6mash9mean6mems8mesa6mesh9mica8mice8mics8mien6mime8mina6mine6mise6name6nema6nice6nims6sain4same6sane4scam8scan6seam6sech9semi6sham9shea7shim9shin7sice6sima6sine4sinh7
3-letter words 58
ace5aim5ain3ais3ami5ane3ani3ash6cam7can5cha8chi8cis5ems5ens3hae6ham8has6hem8hen6hes6hic8hie6him8hin6his6hmm10ice5ich8ins3ism5mac7mae5mam7man5mas5meh8mem7men5mes5mic7mim7mis5nae3nah6nam5nim5sac5sae3sea3sec5sei3sen3sha6she6sic5sim5sin3
2-letter words 26
ae2ah5ai2am4an2as2cs4eh5em4en2es2ha5he5hi5hm7in2is2ma4me4mi4mm6ms4na2ne2sh5si2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.