The letters in SETTLES make 56 words of two letters or more. The longest is SETTLES at 7 letters, and the highest-scoring is SETTLES at 7 points.
No other single word uses all 7 letters of SETTLES. SETTLES has 7 letters: 2 vowels and 5 consonants, worth 7 points before any board bonuses.
7-letter words 1
6-letter words 7
5-letter words 10
leets5seels5setts5sleet5steel5stele5stets5teels5teles5tests5
4-letter words 21
eels4else4eses4esse4lees4leet4less4lest4lets4seel4sees4sels4sets4sett4stet4teel4tees4tele4tels4test4tets4
3-letter words 11
eel3els3ess3lee3let3see3sel3set3tee3tel3tet3
2-letter words 6
el2es2et2ls2ss2ts2
Words are from our open word list and include some game-only words. Rude words are left out of this page; the unscrambler shows every valid word, lets you add blank tiles and filter by length.